E-learning as a modern educational system has certain components, and adopting this system will affect the conditions and characteristics of administrative aspects of the educational systems. Some of the critical educational factors such as requirements/ necessary skills /capabilities/ admission factors and learner capabilities/ characteristics will evolve significantly in this modern educational paradigm. The main objective of this paper is to present a framework for main indices and factors regarding e-learner readiness evaluation and also identifying the learners' skills, capabilities and limitations in a way to enable e-learning system administrators to provide preparation and support services for improving learning quality. In this paper, through a survey of e-learners' readiness characteristics, a framework for e-learners' primary preparation and corresponding guidelines for e-learners' support is proposed which is based on level of readiness. The proposed framework is targeted to academic courses, though its analysis mechanism can be easily workable for other educational courses as well.