There is an increasing need for an integrated test framework which can do conformance and interoperability testing in all layers of e-business standards without any dependence on a specific standard. In this paper a knowledge framework was provided for designing a model for e-business integrated testing by combining identified design factors from testing experience and conducting the CEN (European Committee for Standardization) GITB (Global Interoperability Test Bed) project feasibility study. Also, it was shown that abstracting of test scenarios in a modular manner makes them easily understandable, independent from test beds and standards and, furthermore, more reusable. Embedding a test case tool in the test framework provides the capability of automatic generation of executable test cases, and simultaneously makes them more manageable. A modular test bed design, by considering some interfaces to pluggable adaptors and applying event driven execution model, make it configurable and applicable to the various test types. By embedding management components into the test bed, more controlling and monitoring were provided over the test and its steps as, functional requirements for the current test beds.